AMATH 504  |  Schedule  |  Instructors  |  Content  |  References  |  Prerequisites  |  Grading  |  Calendar  |  Notes  |  Homework  
 
     

AMATH 504


Mathematical Biology II
Spring 2008

Schedule



SLN: 10220
Days: T, Th
Time: 3:30-4:50 pm
Room: Guggenheim 416

Instructors



Name: Mark Kot
Office: 415G Guggenheim Hall
Phone: (206) 543-0908
Fax: (206) 685-1440
Email: kot@amath.washington.edu


Office Hours: M, W
1:00-2:00 pm


Name: Hong Qian
Office: 415E Guggenheim Hall
Phone: (206) 543-2584
Fax: (206) 685-1440
Email: qian@amath.washington.edu


Office Hours: TBA

Content


Course Catalog



Amath 504 is intended as either the third course in the Amath 422-423-504 mathematical biology sequence
or as a standalone course in advanced aspects of mathematical biology.



The primary focus of the course is on spatial models in biology.


Topics to be covered include:

  • the formulation of spatially structured models,
  • reaction-diffusion equations,
  • steady-state solutions,
  • models of spread,
  • traveling waves of invasion,
  • the spread of rabies,
  • integrodifference equations,
  • PDEs in stochastic problems,
  • random movement: the diffusion equation revisited,
  • reaction-diffusion models for chemical reactions,
  • the Smoluchowski theory of diffusion-controlled reactions,
  • Brownian motion and stochastic differential equations,
  • and Kramers theory and evolutionary stochastic dynamics.

References




Useful reference books include:


  • Allen, L. J. S. (2007)
    An Introduction to Mathematical Biology
    Pearson Prentice Hall, Upper Saddle River, NJ.
    
    
    UW Library Catalog
    
    
    
    
  • Brauer, F. and Castillo-Chavez, C. (2001)
    Mathematical Models in Population Biology and Epidemiology
    Springer, New York, NY.
    
    
    UW Library Catalog
    
    
    
    
  • Britton, N. F. (1986)
    Reaction-Diffusion Equations and Their Applications to Biology
    Academic Press, London, UK.
    
    
    UW Library Catalog
    
    
    
    
  • Britton, N. F. (2005)
    Essential Mathematical Biology
    Springer, London, UK.
    
    
    UW Library Catalog
    
    
    
    
  • Edelstein-Keshet, L. (1988)
    Mathematical Models in Biology
    Random House, New York, NY.
    
    
    UW Library Catalog
    
    
    
    Edelstein-Keshet, L.  (2005)
    
    Mathematical Models in Biology
    SIAM, Philadelphia, PA.
    
    
    UW Library Catalog
    
    
    
    
  • Keener, J. and Sneyd, J. (1998)
    Mathematical Physiology
    Springer, New York, NY.
    
    
    UW Library Catalog
    
    
    
    
  • Kot, M. (2001)
    Elements of Mathematical Ecology
    Cambridge University Press, Cambridge, UK.
    
    
    UW Library Catalog
    
    
    
    
  • Mangel, M. (2006)
    The Theoretical Biologist's Toolbox:
    Quantitative Methods for Ecology and Evolutionary Biology
    Cambridge University Press, Cambridge, UK.
    
    
    
  • Murray, J. D. (2002)
    Mathematical Biology I: An Introduction
    Springer, Berlin, Germany
    
    
    UW Library Catalog
    
    
    
    
  • Murray, J. D. (2003)
    Mathematical Biology II: Spatial Models and Biomedical Appications
    Springer, Berlin, Germany
    
    
    UW Library Catalog
    
    
    
    
  • Okubo, A. and Levin, S. A. (2001)
    Diffusion and Ecological Problems: Modern Perspectives
    Springer, New York, NY.
    
    
    UW Library Catalog
    
    
    
    
  • Petrovskii, S. V. and Li, B.-L. (2006)
    Exactly Solvable Models of Biological Invasions
    Chapman & Hall/CRC, Boca Raton, FL.
    
    
    UW Library Catalog
    
    
    
    
  • Shigesada, N. and Kawasaki, K. (1997)
    Biological Invasions: Theory and Practice
    Oxford University Press, Oxford, UK.
    
    
    UW Library Catalog
    
    
    
    

Prerequisites


Amath 422 and 423 are helpful, but not essential.



You should be comfortable with ordinary differential equations.


You must be willing to learn a lot about partial differential equations.

Grading


Homework accounts for 70% of the final grade.



A 10-15 page term paper accounts for 30% of your final grade


Homework problems will be assigned on a regular basis and are due one week from the date of assignment.  


Homeworks must be done alone; they are not group projects!

Calendar


Important Dates

March 31 - Monday - First Day of Classes      
May 26 - Monday - Memorial Day (No Class)      
June 5 - Thursday - No Class      
June 9 - Monday - Papers Due ( < 12:00 pm)      

Notes


Spatially structured models



Spatial steady states: linear problems


Spatial steady states: nonlinear problems


Models of spread


Random movement and diffusion revisited


More discussions on stability and bifurcation


Smoluchowski-Noyes theory of diffusion-controlled reactions

Homework


Homework problems will be assigned on a regular basis and are due one week from the date of assignment.



Homeworks constitute 70% of the final grade.


Write up your homework alone, not as a group!


Mark's problem #2.1 (Due: 4/10/2008)


Mark's problem #2.2 (Due: 4/10/2008)


Mark's problem #2.3 (Due: 4/10/2008)


Mark's problem #3.1 (Due: 4/29/2008)


Mark's problem #4.1 (Due: 5/06/2008)


Hong's homework #1 (Due: 5/15/2008)


Hong's homework #2 (Due: 5/22/2008)


Hong's homework #3 (Due: 6/5/2008)