Inverse Solution Methods and Perturbation Estimates for Radiation Leakage without Scattering David Ketcheson The inverse problem of estimating system parameters from measurements of radiation leakage from a decay gamma source surrounded by a series of concentric spherical shield layers is considered. It is assumed that measured lines are well resolved and that any scattered photons are removed from the line; therefore, scattering is ignored. With this approximation, the transport equation is solved semi-analytically using ray tracing. Gradients of the calculated leakage with respect to the parameters are evaluated either by adjoint differentiation or by differentiation of the ray trace expression for the leakage. These gradients are used in gradient-based root-finding and optimization methods. The resulting methods are able to estimate unknown source and shield thicknesses, densities, and compositions using only measured gamma-ray leakage fluxes. These methods using semi-analytic gradients are compared with existing methods using discrete ordinates calculations and adjoint differentiation. The ray trace derivatives are more accurate and computationally efficient, resulting in a faster and more robust inverse solution. Perturbation estimates for internal interface perturbations are considered, and estimates are developed that are highly accurate over a very large range of perturbations.