Presented at Johns Hopkins School of Medicine, Biochemistry (1/26/99)

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Table of Contents

Protein Fluctuation and Dynamics

Protein Denaturation by Urea

Hydrogen Exchange in RNas A

Analyzing Spectroscopic Measurements

Hydrogen Exchange Rates Reflect Protein Fluctuation

Fluctuations of Cytochrome c

Internal Fluctuation & Global Folding-Unfolding (A Discrete Kinetic View)

Individual & Cooperative Local Fluctuations

Temperature and Denaturant Unfolding of Cytochrome c

Protein Folding & Molten Globular Intermediates

Summary and Future

A Computer Simulation Program

Author: Hong Qian

Email: qian@amath.washington.edu

Home Page: http://www.amath.washington.edu/~qian